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We mentioned GABA briefly in our GHR-15
review article. Let's take a closer look now at GABA.
GABA (gamma-aminobutyric acid) is the most important
and abundant inhibitory neurotransmitter in the brain (it's actually
an amino acid classified as a neurotransmitter). It helps induce
relaxation and sleep. It acts as a "balancer" for the
brain where excitation of the brain is balanced with inhibition.
In addition to it's 'balancing' effects, GABA
stimulates the anterior pituitary, leading to higher levels of Human
Growth Hormone (HGH), and if you didn't know, HGH is very anabolic
(muscle building) and lipotropic (fat preventing). So, GABA indirectly
enhances these 2 positive effects. Let's take a quick look at the
benefits of Human Growth Hormone:
- HGH is shown to have anti-aging effects
- Higher levels of HGH leads to less body fat
and also better lean tissue-stored fat ratio
- HGH level decrease with age, so supplementation
is beneficial
- Helps lose fat and improve lean muscle
GABA Research and Studies
There are many studies done on GABA and GABA effects,
and studies have show GABA to promote significant increase in plasma
growth hormone levels.
One study (conducted by First Medical Clinic at
the University of Milan in Milan) found that 90 minutes after GABA
supplementation, HGH levels increased 5 times. This research studied
19 subjects who took GABA compared to 18 placebo subjects, and 5
grams of GABA was administered orally to the GABA group. After 90
minutes HGH levels in the GABA group were found to have increased
by 5 fold.
Research shows that at least 2 grams of GABA should
be taken for it to be effective. 5g is shown to be more effective,
and the effectiveness of GABA is maxed out at 18 grams. There are
studies done on GABA where it's administered either orally or intravenously.
Taking GABA orally is not as effective as taking it intravenously;
however it's more reflective of expected real world results, as
most GABA supplements are designed to be taken orally. Despite this,
GABA is effective even when taken orally.
GABA Side Effects
There are few if any side effects of GABA. Some
users have experienced some mild tingling sensations around the
face and neck area after supplementing GABA. Some users also notice
a brief and milk change in heart rate or breathing patterns. These
GABA side effects quickly disappear and are not harmful. Not everyone
experiences these side effects, so you may, or may not experience
these GABA side effects.
GABA also has a slightly sedative effect, which
makes it ideal to take before going to bed.
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